s. pneumoniae — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40417	Ethylhydrocupreine hydrochloride	Optochin hydrochloride	Antibacterial , Parasite
	Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a derivative of quinine with antimicrobial activity against Streptococcus pneumoniae.Ethylhydrocupreine hydrochloride has antimalarial activity with an IC50 of...		Antibacterial , Parasite
T2331	Solithromycin	OP-1068,CEM-101	Antibacterial , Antibiotic
	Solithromycin (OP-1068) is an orally bioavailable antimicrobial agent that inhibits cell viability, protein synthesis, and growth rate of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus aureus, and Haemop...		Antibacterial , Antibiotic
T72330	Antibacterial agent 19
	Antibacterial agent 19 exhibits strong activity against K. pneumoniae, (M-R) S. aureus, and (M-R,V-R) S. aureus, demonstrating minimum inhibitory concentrations (MICs) of 0.022 mg/mL for both K. pneumoniae and (M-R) S. a...
T62773	OX11
	OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa and E. coli bacteria.
T37721	Dihydronovobiocin
	Dihydronovobiocin is a coumarin antibiotic and derivative of novobiocin .1It is active against the bacteriaS. aureus,S. haemolyticus,D. pneumoniae,S. typhosa,K. pneumoniae, andP. multocida(MICs = 0.6, 2, 0.6, 10, 10, and...
T36032	Desotamide
	Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs = 16, 12.5, and 32 μg/ml, respectiv...
T38333	Corynecin I
	Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneu...
T36028	Desacetylcefotaxime (potassium salt)
	Desacetylcefotaxime is an active metabolite of the cephalosporin antibiotic cefotaxime .1It is active against 60 clinical isolates derived from patients with meningitis, includingH. influenzae,S. pneumoniae,S. agalactiae...
T38021	Obafluorin
	Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.1 It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all). \|1. Pu, Y., Lowe, C., Sailer, M., et al....
T38334	Corynecin III
	Corynecin III is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. ...
T75516	Seconeolitsine
	Seconeolitsine, an antibiotic and new antimicrobial agent, inhibits the growth of S. pneumoniae and possesses activity against topoisomerase I (TopA), effectively inhibiting TopA's relaxation activity with an IC50 value ...
T69058	OM173-αA
	OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M. gallisepticum, M. pneumoniae, and S. aureus. OM173-αA also inhibits the growth of the plant pathogenic fungus P. oryzae and several s...
T38259	Phenelfamycin E
	Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) inc...
T72532	Ethylhydrocupreine	Optochin
	Ethylhydrocupreine (Optochin), a quinine derivative, exhibits antimicrobial properties against S. pneumoniae and antimalarial capabilities targeting Plasmodium falciparum with an IC50 of 25.75 nM. Additionally, it acts a...
T37888	Desacetylcephapirin sodium
	Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin .1 Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus with MIC values of 120, 24, 34, and 0.42 ...
T32669	Leucomycin a5	Leukomycin A5,Turimycin H4
	Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not a...
T81737	MurF-IN-1
	MurF-IN-1 (Compound 7) is an inhibitor of the MurF enzyme, exhibiting an inhibitory concentration with a pIC50 value of 5.19 in assays targeting Streptococcus pneumoniae MurF [1].
T38086	Neohydroxyaspergillic Acid
	Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. my...
T36181	Quinaldopeptin
	Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/...
T39175	CSP1
	CSP1 is a highly potent and selective agonist of the ComD1 receptor, exhibiting an IC50 value of 10.3 nM. It represents a major variant of competence-stimulating peptide (CSP) and plays a crucial role in regulating the g...